Weekend Reading
Writing worth reading 23rd/24th Aug 2025
Why don’t we know how antidepressants work yet? by Andy Extance
“As such it might seem strange that researchers like Hashemi still don’t fully understand how SSRIs work, and why they work better for some patients than others. In fact, researchers have struggled to balance the drugs’ benefits with their shortcomings for decades. In 2004, Chemistry World reported findings that they only work slightly better than taking an inactive placebo. At the same time, concerns around increased risk of suicide among patients, especially children, taking SSRIs came to prominence. SSRIs also have other potentially serious side effects…”
Why Did No One Say Anything? by Konstantin Kisin
“The investor Charlie Munger, who is Warren Buffet’s right-hand man, said “Show me the incentives and I’ll show you the outcome”. What no one realized at the time is that social media rewards certain types of communication. And whatever you reward, you get more of. Social media rewards complaining, outrage and victimhood so it produces complaints, outrage porn and victims…”
Moore's Law for Everything by Sam Altman
“Because we are at the beginning of this tectonic shift, we have a rare opportunity to pivot toward the future. That pivot can’t simply address current social and political problems; it must be designed for the radically different society of the near future. Policy plans that don’t account for this imminent transformation will fail for the same reason that the organizing principles of pre-agrarian or feudal societies would fail today…”
Founders (need) Focus
This week we shared that we’re starting Founders Focus, a new membership program from 9others; a space for you to carve out time to work on the hard things that really matter. Check out the announcement here.
What does it do?
Founders Focus keeps you focused, accountable and connected.
Who it’s for?
Founders Focus will suit Solo Founders, Remote (Co) Founders, and Freelancers, CxOs and Side Hustlers.
Qs?
Read more and check out the FAQs on the 9others Notion, here.
We hope you’ll join us.